MPEGed is a handy and easy to use application that enables you to find errors in the aspect ratio headers of MPEG videos. Delivered inside a lightweight package, this application works with MPG, MPEG and M1V files, enabling you to fix incorrect header properties of your videos.
The application features an intuitive layout of the interface, which makes it very easy to work with. In order to ignore certain file types and only look for MPEG videos, you can enter the desired file types to look for within the designated area of MPEGed.
You start by selecting the directory to search in and MPEGed will display all the files it finds, considering the filtering settings you configured. Matching files are displayed in a different pane, enabling you to analyze each of the videos individually.
MPEGed scans each video file for a valid header within the first 65332 bytes, displaying all the identified errors.
Using the ‘Property Editor’ section, you can change the video resolution and the playback rate, as well as change the fullscreen aspect ratio. MPEGed can match the aspect ratio with the video resolution and suggest a specific value for you to select (PAL, NTSC).
What MPEGed actually does is scan a whole folder for MPEG files and verify the aspect ratio header for each, giving you the freedom to modify the header properties without making a compromise on quality. It definitely takes less time to modify the video properties with MPEGed, rather than re-encoding it.Maprotiline in advanced schizophrenia. I. Efficacy and safety.
A double-blind study was carried out to determine the efficacy and safety of maprotiline, a new noradrenergic antidepressant. One hundred and thirty inpatients with schizophrenia or schizo-affective disorders were randomly assigned to receive maprotiline 50 mg/day or placebo for 6 weeks. Efficacy variables included the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impressions Scale (CGI), the Hamilton Rating Scale for Depression (HRSD) and the Young Mania Rating Scale (YMRS). Safety variables included the number and type of adverse events and a clinical laboratory profile. Maprotiline was well tolerated, and few adverse events occurred. The efficacy of maprotiline was good, and statistically superior to placebo, with a superiority of 25-40% on the total PANSS score and on each PANSS factor. A greater than 50% improvement in the CGI global severity and improvement on the 384a16bd22
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The urokinase plasminogen activator receptor (uPAR, CD87) is a member of the scavenger receptor cysteine-rich superfamily that is required for cell adhesion, migration, and invasion. In addition, uPAR may play a role in cell growth and angiogenesis. We have demonstrated that both the cell-surface and the secreted form of uPAR are trans-membrane proteins. The membrane domain of uPAR consists of a single membrane-spanning region. Furthermore, this region contains a consensus sequence for N-linked glycosylation that is conserved among all uPAR molecules. Accordingly, the uPAR of different cells and tissue may have distinct posttranslational modifications. Urokinase-type plasminogen activator (uPA) activates the latent form of uPAR. We have also shown that the uPAR-uPA complex functions as a ligand for the integrin alpha(v)beta3. In addition, the uPAR-integrin interaction is required for cell adhesion. The uPAR/integrin interaction is also important for cell migration. Soluble uPAR or uPA blocks cell adhesion and migration on uPAR- and integrin-specific matrix substrates, respectively. These findings, in addition to the well-established function of uPAR in proteolytic events, make uPAR a key player in cell adhesion and migration. The urokinase receptor is also required for cell adhesion and migration in the chick embryo. In addition, the uPAR-uPA-alpha(v)beta3 system is important in the in vivo adhesion of metastatic tumors to the extracellular matrix. Based on these results, we propose that uPAR may function